 The study investigates a technology acceptance model, TAM, specifically designed for primary health care applications of mobile health, mHealth, apps. The results show that perceived usefulness, attitude toward using, promotion of health, perceived ease of use, and health benefits are significant factors in predicting behavioral intention to use eHealth apps. Gender was found to moderate the adoption of mHealth apps in Spain. The study suggests that communication campaigns for these apps should emphasize the usefulness of eHealth as an agent for transforming attitudes. While more health benefits are obtained, ease of use becomes greater. This article was authored by Pedro or Palo Sanchez, Jose Ramon Sora, Miguel Angel Rios-Martin, and others.