 Lermide-Duclo disease, LDD, is a rare condition of the cerebellum, typically characterized by a haemartominus lesion of the posterior fossa. It is most commonly seen in people aged between their late 20s and early 40s. Although it is considered a low-grade tumor, there have been reports of malignant transformation. Genetic counseling should be offered to patients diagnosed with LDD, as they are at increased risk of developing other types of cancer. Additionally, since LDD is often associated with Cowden syndrome, a multi-system autosomal dominant hereditary disorder, it is important to consider this when making a diagnosis. This article was authored by Ariba Hatik, Usman Hassan, Noreen Akhtar, and others.