 Thank you very much. The first thing I want to say is that the Brain Foundation supports younger researchers and I'm not the primary chief investigator. Theo was an honest student of mine many years ago and in my retirement I've come back to do research and support his activities. So you can imagine how pleased I am that the Brain Foundation supporting his research and I'm giving my labour in the lab for this project I'm talking about today. Now following on from the exciting findings we had from the previous speaker and award, we're interested in brain tumours. Every day in Australia four people are diagnosed with a brain tumour. Some of these are benign but unfortunately many of them are malignant and patients go through surgery, radiation therapy, chemotherapy and new experimental drugs but unfortunately in the last 20 or so years only about 23% of these people reach five years from diagnosis and those that do survive have terrible side effects from these chemo drugs and the other drugs they're treated with. So what we want to do is find ways of killing these cancer cells that are much better tolerated and in Theo's lab they're interested in cell signalling and what they found is with particular set of molecules they could stimulate more normal activity in these cells and it kills them. Now these molecules are not approved for use in humans but they have the same sort of physical properties as many drugs that are actually used in the neurologies for you. In fact one drug is used for treating depression and a number of other drugs approved for Alzheimer's disease. So what we want to do is short track using already existing FDA approved drugs to kill cancer cells and we hope that with a combination of these already approved drugs and the mechanism that we find that actually kills these cells we will be able to give patients a better outcome with much lower degree of symptoms. So we can imagine a situation if for example a drug that was used to treat anxiety was given to a patient with brain cancer will have a dual benefit one treating the anxiety but also helping to kill the cancer. So I'm very pleased to accept this award for Theo who is much younger than I am and thank the Brain Foundation because when I joined the lab a few months ago I was looking at the budget and thinking this works really good how are we going to find money and Theo has managed to convince the reviewers. So I'm very very happy for him.