 Polylactic acid, PLA, has been widely studied for use in bone tissue engineering, BTE. This study aimed to improve the mechanical and biological properties of PLA by adding titanium alloy, T64, and subjecting it to plasma treatment. The resulting scaffold had improved mechanical properties, including increased ultimate compressive strength and compressive modulus, as well as better flowability and surface characteristics. Furthermore, the addition of T64 resulted in improved cell adhesion, proliferation, and differentiation, suggesting that this scaffold could be used in BTE applications. This article was authored by Masood Zari, Motohara Shabani Daga, Mardi HaSanzadeh Husson, and others.