 Exoskeletons can provide assistance to people who struggle with walking up slopes or hills. Recent research has shown that these devices can reduce the energy expended when walking on flat ground, but it is unclear whether this benefit extends to inclined terrain. In order to optimize the amount of assistance provided by an exoskeleton, researchers used a human-in-the-loop optimization approach to determine the best torque levels for different inclines. The results showed that the exoskeleton was able to reduce the energy expenditure required for walking on inclines by up to 50%. This suggests that exoskeletons could provide significant assistance to people struggling with inclined terrain. This article was authored by Patrick W. Franks, Gwendolyn M. Bryan, Ricardo Reyes, and others.