 This study investigated the contact angle between the implant surface and blood samples from beta-thalassemia major, BTM, patients and healthy individuals. The contact angle was measured using imageJ software with a specific contact angle plugin. No significant differences were observed between the contact angles of the two groups. Therefore, it was concluded that the rheological properties of BTM patients did not affect the wetability of the implant surface. This article was authored by Ali Tamilsai, Hasan Yuney Yilmaz, Gherkin Ansel and others.