 Chronic obstructive pulmonary disease, COPD, is a major cause of death worldwide, with the majority of cases being caused by smoking or exposure to air pollution. Recent studies have shown that the lung and gut microbiomes are linked, with changes in the composition of either microbiome having an effect on the other. Research suggests that these microbiomes may play a role in the development and progression of COPD, but further investigation is needed to determine how they interact and what treatments could be used to target them. This article was authored by Efstathios Caracocides, Herania Escazio and Constantino Zygurgliani's.