 Phytodynamic therapy, PDT, using 5-aminolevulinic acid hydrochloride, ALA, and light-emitting diode, lead, light energy with a wavelength of 635 nanometers effectively reduces the high rate of recurrence for intra-anal rectal warts, achieving a complete clearance rate of 76.1% in 46 patients. However, pain remains a challenge for the therapy, with an average visual analogue scale, the AS, pain score of 6.96 plus or minus 1.41 points. This article was authored by Wei Zhao, Xiaofeng Shan, Changliang Wang, and others.