 In this study, we found a strong correlation between the percentage of C4D positivity in renal biopsies and the severity of IGAN. This suggests that C4D may be a useful marker for monitoring disease progression and predicting the course of IGAN. Further research is needed to validate these findings in larger samples. This article was authored by Hamid Nasri, Ali Amadi, Mahmoud Rafi and Kopi, and others.