 COVID-19 associated coagulopathy is characterized by hypercoagulability and hypofibranolysis from the onset of illness in patients with moderate to severe acute respiratory failure admitted to an intensive care unit ICU. This condition is associated with increased risk of death and is more pronounced in patients with higher disease burden and in those who do not survive. This article was authored by Anabella Rodriguez, Thiago Diaz-Dominguez, Gustavo Nobor Jesus, and others.