 This study found that trust in the government was high at the beginning of the pandemic, but it decreased over time. Perceived vulnerability and an intention to adopt protective measures also increased throughout the pandemic. Trust and perceived vulnerability were associated with an intention to adopt protective measures in general only during the first period. Higher levels of trust and perceived vulnerability were associated with an intention to receive vaccinations. Respondents wanted to receive information about infection prevention from municipal health services, health care providers, and the media. The Dutch response to the H1N1 virus was relatively muted. This article was authored by Oudhorf Jürjen, Boagene Desiree JMA, Timmermans Danielle R.M., and others.