 The study aimed to understand the perspectives of young men who have sex with men, YMSM, for a mobile health, mHealth, tool designed to facilitate human papillomavirus, HPV, vaccination, recruiting participants on a social sexual networking app and using conventional content analysis to analyze focus group data. The study found that YMSM had varying levels of HPV knowledge and utilized apps for various purposes, but desired credible, relatable, secure, and easy to use interfaces that provided sexual health and HPV information in a positive context. A culturally relevant youth-driven approach was identified to facilitate HPV vaccination and sexual health among YMSM. This article was authored by Holly Bfontono, Joshua G. Rosenberger, Caitlin T. McNair, and others.