 Recent studies suggest multiple microRNAs, MyRNAs, are involved in the neuroremodeling process. Targeted MyRNAs delivery for amplification of neurogenesis is promising in promoting the prognosis after ischemia. RVG exosomes loaded with MIR-124 promoted cortical neural progenitors to obtain neuronal identity and protect against ischemic injury. This article was authored by Jelly Yang, Shofeng Zhang, Xiang Jieqian, and others.