 8-week high-intensity interval training, HIIT, attenuates type 2 diabetes, T2D, induced cognitive impairments, CI, in rats, but the effect is sex-dependent, with the diponectin and leptin playing a key role. This article was authored by Mohamed Amin Rajazadeh, Amir Hossain Moslemazadeh, Mahdi Sadat Hossaini, and others.