 This systematic review found that COVID-19 and mucormicosis co-infections are common with the nose, cranial sinuses, orbital cavity, cerebrum, lungs, and heart being the most commonly involved organs. Pre-existing diabetes mellitus and corticosteroid use were identified as risk factors for this co-infection, but other underlying conditions and immunomodulatory drug use were also present in several cases. Aspergillus was the most commonly reported microorganism causing further co-infections in patients with concurrent COVID-19 and mucormicosis. The overall mortality rate for these cases was 33.6%, highlighting the importance of early diagnosis and appropriate treatment plans for patients with underlying comorbidities, immunocompromised patients, and those receiving corticosteroids to prevent mucormicosis co-infection. This article was authored by Syed Ahmad Syed Al-Anagi, Amarali Kareemi, Ali Reza Barsagari, and others. We are article.tv, links in the description below.