 So now it's my pleasure and honor to present the Linus Pauling Institute Prize for Health Research Now this prize is awarded in recognition of innovation and excellence in research relating to the roles of vitamins essential minerals and phytochemicals in promoting optimum health and preventing or treating disease and the roles of oxidative and nitrate stress and Antioxidants in human health and disease. So that's the name of the award. That's all of what's in there Now that's not the only thing and this year thing. This becomes a little bit more prominent because the prize also recognizes successful efforts to disseminate and implement knowledge on diet lifestyle and health to enhance public health and reduce suffering from disease So this is the outreach component that comes with doing research now just As a little bit of background the LPI prize for health research is awarded every other year and at this conference So the diet and optimum health conference So in the 20-year existence of the Linus Pauling Institute, the prize has been given eight times So it's not done very often Three of the past recipients are present today and they are Dr. Bruce Ames Dr. Mark Levine and Dr. Helmut Siege would you please stand up and be recognized now you're recognized from these names That these and the other recipients have made outstanding contributions to the field Named by the prize. So this is really this is a very high standard for receiving this award Now, how do we get to? Identify the award. So there's a procedure for this now because this is an LPI what so what we normally do We convene a committee And the committee collects nominations and then the faculty deliberates about the nominations So based on these deliberations the committee decided to give the 2017 Linus Pauling Institute prize for health research By acclimation of the faculty of the Linus Pauling Institute to Dr. Paltz Frey Not yet. So Paltz There is a Lodatio Yeah, so it takes me a while to read all that because there's so much to say That I will read it first and then you come up and then you'll get the prize, okay So this will take me a while. So the committee has comments, of course and here are some Comments on the committee. So Dr. Frey built two outreach programs at the Linus Pauling Institute that are locally regionally, nationally and internationally recognized These programs disseminate and implement knowledge on vitamins minerals and phytochemicals in relation to diet and health and lifestyle So this is the exact wording that you find in the name of the award so the first outreach program is the healthy youth program and Simone, yeah, you are there is the first is the founding manager of that Core or the the program the health youth program and Candace, where are you? See is currently at the manager of the of the health youth program Now to give you an idea of the scope and size of the various outreach programs And when I came on board and say what you do all that how is there enough hours in the day to do all that? And there's actually very small staff to take care of all these programs So the hip program is running What all the stuff that we already have partnerships with community organizations including Samaritan health services Lin Benton Lincoln partnership for health strengthening rural communities Rural families Lin Benton health equity Alliance will allow my neighborhood housing services Oh issue Benton County Extension service Benton soil and water Convers conservation district Corvallis environmental center the boys and girls Club of Corvallis and The College of osteopathic medicine of the Pacific Northwest See all of this. There's so much. What's going on. This is just enormous So through these community partnerships the hip programs have been able to reach upwards of 1200 Children and families just in this past year So you can see over all these years how many how many kids they have helped About nutrition and healthy lifestyle. This is just enormous So furthermore the hip internship and volunteer programs provided more than 50 positions for OSU students So this is also King of that and if I have five undergrad students my lab poor they keep me busy They have 50 students To gain leadership experience to build professional skills You know, this is OSU is very much into leadership skills and and you provide all the the hip provides all them the skills to do this for these young children So that's the healthy youth program and the second outreach program is the micronutrient information seller And we call it the mick. So that's the if I say mick. I mean, that's the micro information information center So the mick disseminates unbiased evidence-based knowledge on vitamins minerals and phytochemicals now The information that's important is freely available and that's important because you know But what is today is freely available? Not much anymore On the mick website. So dr. Fry Assisted first by dr. Jane Hickdon and more recently by dr. Victoria Drake Victoria. Where are you? Please be recognized. Yeah, that's Vicki does all that Secured funding for the mick through corporate sponsorships charitable giving and grants So this is again sponsorships are very important to keep that program alive So that people the public has free access to a lot of valuable and unbiased information Now just last year and of course I didn't I Didn't do this because it already started many years before so after several years of planning The mick team launched the new health and disease section on the website that organizes nutrition information by health and disease topics So in the normal you make you start with the minerals and the vitamins and the phytochemicals and what? What are the health benefits and now they have a second site where actually you go the other way you go from disease and health and what? Nutrients are beneficial in those conditions Now what the that website is doing is summarizes take-home messages in a bullet point format and And incorporates nutrient flashcards and infographics to reinforce important concepts So in the past year and this is another thing that I didn't know about when I came the mick generated over 1.7 million sessions and 1.3 million visitors worldwide and that's just one year Now moreover the mick is available in Spanish We have a collaboration with people in Chile and also I sign actually the MOU this year for The MOE that we do this way in Japan with the folks in the negata So soon it will also be the mick will be available in the in Japanese. So this is just enormous Now this is only about Outreach so now I'm talking about research and I can probably give a talk for a whole hour. So I have no time for that So now I would like to quote dr. Fry's remarks on the state of nutrition and this is not bad as you When he started his career in molecular nutrition and do you remember what you said So dr. Fry said something went in so that's nutrition Yeah Something possibly resulted from it. Yeah, so that's the health benefit Yeah, but what happened in between was largely a black box and what was lacking was Mechanisms and that is what dr. Fry focused on in the LPI And I think we're the Institute that really focuses on mechanism of action of vitamins and nutrients So that is the how we started out and our ball started out Now at the end of the career because you decided to do something else in life So I could so during his scientific career dr. Fry published 355 papers That's enormous. What is more? Impressive is that they were cited 19,000 times This is enormous some people don't live long enough to get so many citations and now what some people most people don't live long enough So his papers have made an enormous impact in the field of molecular nutrition as indicated by the Hirsch index And that is 71 That's very high if you have ever submitted an application or you need to do a job interview and 71 is just That's just enormous. So I can testify that a Hirsch index of 71 is exceptionally high Now, let me give a few examples of what the research was about So dr. Fry has made several important discoveries on the role of vitamin C in cardiovascular disease initiation in progression So in 1995 so there's many years ago He published a paper in the journal biological chemistry reporting that vitamin C protects low-density lipoprotein against athrogenic modification Yeah in 1999 dr. Fry published a paper together with dr. Anita car. Would you please wave and be recognized? Yeah You were together at the time and it was in the audience today with a provocative title Does vitamin C act as a pro-oxidant under physiological conditions? So this just this morning I heard people asked that very same question. So this is nothing new dr. Fry thought about these things Many many years ago Now that's not only that way. This is only vitamin C So dr. Fry pioneered and the use of f2 isoprostanes as markers Of in vivo oxidative stress So in 1995 again many years ago He authored a paper on using plasma f2 isoprostane levels to demonstrate that smoking is a cause of oxidative stress You know, you think it is you take it for granted, right? If you smoke you got after this about how do you measure that? No, Bolts fry developed methods that we can actually measure from a plasma sample. What is oxidative? How do you quantify that? Now this seminal paper was cited over a thousand times. Yeah, you didn't know that, but it's that many So dr. Fry and his lab team at the Linus Pauling Institute have made important inroads into the mechanistic actions of phytochemicals and polyphenols in particular So he has helped LPI principal investigators determine mechanism of action of Phytochemicals to mitigate chronic low-grade inflammation that lies at the root of many age-related diseases So under the leadership of dr. Fry LPI researchers have broken new in ground in mechanistic research on catechins and tea Cursatin in onions So farofane and broccoli and xanthoyumolin hops, you know, we're all together in this and I remember every week We had these faculty meetings discussing this and every time you went to these meetings There was always some idea that came out as a yeah now. I finally got an answer to my problem And that was very good at that is just very good Now the findings of that body of research have generated new knowledge in preventing pathological conditions such as cancer metabolic syndrome neurodegenerative disease and cardiovascular disease So LPI researchers could not have made those discoveries without the research in intellectual infrastructure that dr. Fry Built and I'm now using dr. Hagen's words from the first day From scratch because there was nothing there. That's enormous So I would like to close with another quote from dr. Fry so he said While ago doing basic research is one thing it's important, but it's not the end of the story It is equally important to come out of the ivory tower and Really help people make the right decisions regarding the use of diet and diet with supplements for their health That's very true and that really exemplifies what the award is all about So in this concluding sentence, I would like to ask dr. Paltz fry to come to the podium and receive the award Congratulations. Thank you so much Well There's more Do you know there used to be money involved in this? Well, I'm not going to give you a check. I know that But I can tell you that a donor has come forward and the donor has made a sizable donation Into your Bolts fry and doubt fellowship fund and that benefits students for for many years to come I need to tell the audience that I can't say anything about the amount nor the identity of the donor because that donor wants to be Anonymous so let's Bolts. Thank Bolts one more time