 Abstract flaxseed, linemusetitisimum L, is an ancient perennial plant species regarded as a multipurpose plant owing to its richness in omega-3-polyunsaturated fatty acids, PUFA, including linoleonic acid, ALA. The extensive biochemical analysis of flaxseed resulted in the identification of its bioactive lignin compounds with potential application in the improvement of human health. Flaxseed oil, fibres, and lignin's exert potential health benefits including reduction of cardiovascular disease, atherosclerosis, diabetes, cancer, arthritis, osteoporosis, and autoimmune and neurological disorders that have led to the diversification of flaxseed plant applications. This comprehensive review focuses on flaxseed oil as the major product of flaxseed with emphasis on the interrelationship between its chemical composition and biological effects. Effects reviewed include antioxidant, anti-inflammatory, anti-microbial, anti-cancer, anti-elsa, anti-osteoporotic, cardioprotective, MET. This article was authored by Samir Al-Madagi, Nagla S. Ashmoui, Ayat Mambu, and others. We are article.tv, links in the description below.