 The center of a great world scientific activity, not only to carry out functions of the organization, but also as a center of important research in the uses of atomic energy. For over 60 years, the IAEA's eight nuclear applications laboratories have provided applied research into human health, food security, and environmental protection. The laboratories based just outside Vienna have shared their discoveries with more than 150 member states and trained thousands of visiting scientists from around the world. Over the years, this work has only become more relevant, with research into emerging zoonotic diseases like COVID-19 and global issues like cancer care and climate smart agriculture. In 2014, the Renewal Initiative was launched to provide much needed modern and expanded facilities at the site. Over 39 million euros was raised to make this vision a reality. All three buildings delivered under the first stages of the initiative are now in use. These include a new insect pest control laboratory, a linear accelerator facility, and a new building with laboratories focusing on animal production and health, food and environmental protection, and soil, water and crops. The project is now gearing up for its final milestone. An updated decimetry laboratory, new greenhouses, and a brand new building for the remaining three facilities. The plant breeding and genetics laboratory helps strengthen food security and improve climate smart agriculture, with crop varieties resistant to disease, drought and other harsh conditions. The Nuclear Science and Instrumentation Lab develops techniques for a wide range of operations, from environmental monitoring to the preservation of cultural heritage. And the Terrestrial Environment Laboratory provides expertise, training and support dealing with radioactive, industrial and other pollution. The stage of the project will complete the overhaul of this unique scientific centre and prepare the CyberStore facility to face the emerging needs of the IAEA's member states. New challenges arise and the work of the IAEA becomes ever more essential. The IAEA labs in CyberStore are an indispensable part of our effort. Through the support of our member states, we can make sure that our laboratories are up to the challenge.