 Interested in the anti-aging performance enhancing benefits of NMN watch this our first caller is Joe from New Jersey What's up Joe? How can we help you? Hey, what's up? What's up? Cool, so I was wondering what are your thoughts on NMN? Like do you guys take that? Have you taken it is it worth it? Okay, what is that a sex toy? What is that? What is it? What is it? It's like BDSM, except it's Acronym for the bondage part a sexual move. What is that? Yeah, you got it help me with okay, where did you hear about this and I got another question first I want to ask you Joe Joe how long have you been consistently like no breaks been training and what does your workout look like? Let's start with that first So I'm 41 I guess I've been like active and training since I was like 20 good deal So super consistent you would say Yeah, I do everything. I'm not I'm not I don't go to the gym, but I I do run a lot I I lift weights I do like calisthenics push-ups pull-ups awesome And then nutrition wise, what does that look like? What does your diet look like? How many grams of proteins carbs and fats are you eating? I don't really pay attention to that. I'm I'm actually a student of Ayurveda. Oh good So I just eat I eat really well Okay, but protein maybe like Maybe 60 grams a day maybe okay, and what is your how many hours of sleep? Do you have every night you have a sleep routine before you go to sleep? No sleep routine. I just passed out at like like 10 o'clock. I wake up at like 5 30 Yeah, okay, so I don't think you should waste your money on any of these supplements that like for example What you're talking about. I mean there's some studies that shows it might it does this that I mean, is it gonna move the needle? No, I'll tell you what'll move the needle Joe Start paying attention your grams of proteins fats and carbs I would look at your workout. I would definitely pay attention to sleep But you know supplements like this kind of look and by the way this is coming from a supplement like I'm a I will Admit a young fanboy. I'm a junkie when it comes to supplements. I try everything I use everything but when I step outside of myself and my you know my my addiction to these things I mean it's not gonna do it's not gonna do anything for you like, you know, you're eating 60 grams approaching a day I bet if you bump that a little bit you'd probably I know you would see better results than what you're seeing now Or what you're seeing what you would see from supplementing with with NMM. I don't remember the acronym, but you know Nicotinamide mononucleotide There you go. I had a written up that I know that's a precursor to NAD Yeah, yeah, and I've heard all the all the fuss about it, you know shows that it well listen NAD There's a company that tried to pay us to Advertise for NAD and none of us were impressed with the research around it as far as the real benefits Here's the thing That's why I wanted to ask you guys because there's so much information out there and it's all it's all confusing Yeah, you know here's a thing with I mean for me that the way I kind of look at tease it out I mean Sal's right if you're if you're not tracking sleep or not tracking your macros I mean you're gonna get you're gonna see more gains in in whatever you're pursuing just by by simply doing that There's the other side to your 41 years old You're probably pretty established if you got a decent income and you can burn You know a few hundred bucks a month and a big deal And so long as all the research is pointing that it's not harmful or dangerous then fuck it play with it I don't care, you know, that's kind of how I would I would treat it But I the when we address supplements on here There's always so many other things that that somebody who's looking for the competitive edge or wants more from their workouts There's so many other things that we can do that doesn't require you spending any money that will give you way more return Than anything that's on the market minus, you know illegal drugs, right? Yeah, obviously well even drugs that you put someone in anabolic steroids with a shitty diet You're right. It's bad training and they're not gonna do as well as someone with good diet good training Who's natural and that's anabolic steroids, you know, and here's the other thing to pay attention with studies Look, you you practice Ayurvedic medicine. I'm probably preaching to the choir right now But on a on a you know, we could on a physiological level we could say wow increases antioxidant You know activity and mitochondrial function. Okay, but what does that mean because there's so complex There's so many Downstream and upstream things that get affected when you change something so I can I can say to some I can look at a test and say wow Protein synthesis went up, right? But what does that necessarily mean? It couldn't mean we're building more muscle We don't know yet. It could mean It could mean a lot of different things can be more inflammation depending on the context of the of the individual so In NAD, you know, and it's precursors. There's studies, but it's not look I'll tell you what if you want to improve mitochondrial function, which is one of the main selling points Supplement with creatine creatine is Thousands and thousands of studies have been done on it over the over the past few decades It's very well studied Some of these other compounds not so much and many of the studies that they have are done on animals and very few are done on humans Not saying it's dangerous. Probably not, but it's it's kind of a waste of time unless you're admittedly like me Where you just like this is fun I like to mess with things in which case it's a go for it and kind of see what happens But if I'm coaching you if I'm training you you know I'm if you're perfect in everything that's one I'll say all right, let's have some fun if you're not perfect and everything was a well Let's focus on this other stuff first because you're gonna get way more out of you know changing these things then just you know Been taking this this I'm out just cuz it's like I have to say I'm having fun with NADs. I'm done Justin takes NADs all the time NADs out my mouth that's pretty much it so now I want to give you something because I know we kind of hammered you a Little bit. It sounds like your fitness goals are overall fitness and performance. Is that correct? Yeah, okay. Do you just curious about it? Yeah, I actually started taking creatine because you guys so that's the that's the one supplement I think that'll make I definitely will kick the crap out of and NMM in terms of you know mitochondrial function and performance Do you have maps performance because I think that would be a good program for someone like you No, but I'll check it out. We'll give it to you. We'll send that to you Joe No problem. All right, man. Thanks for calling in. I appreciate it. Thank you. Thank you Yeah, dude the supplement industry's really did a number on I knew I knew right where you're going You know, yeah, right where you start asking them. It's sunlight. It's so true outside And I know we I know I could have gone down a list of like 15 and I know some people that like drop in that Haven't listened to the the all of the podcast and stuff like that would be like Well, you guys are sponsored by supplements and you talk about some of it It's like yeah, but in the context of if you're doing this then okay here Or if you're missing these things then this makes sense like not like you should take this to build muscle Or this is the best thing for burning body fat or this is you know It's like there's so many other boxes that you can check first before you go Try some new supplement that's on the market right now that everybody is touting as the next best thing for whatever You know, everybody thinks they're eating well till they start tracking it. Yeah, that's you That's a big factor that I've always found with people that are really interested in supplements It's always like looking for that like last bit of edge. They haven't really You know done the work part of they're looking for the shortcut Yeah, they're looking for the shortcut They're looking for something that is going to give that type of return that you're talking about But they don't want to do that work and it's like listen if you really want to see some benefits man Let me tell you, you know track track your food and dial in your sleep routine And there's nothing on the market that I could give you a movie much further nothing and again The the so the functions of human body are so complex. We we we know some of it We know we know the tip of the iceberg We don't know majority of how things interact with you because there's so many things that influenced By other things that we could change one thing and measure that and say it's good and not realize This is why so many pharmaceutical drugs get pulled off the market because it does its targeted thing and we find out later Oh shit, it increases risk of stroke or looks like this might make Alzheimer's more prevalent So we have to pay look I'll give you an example right mTOR We measure mTOR and when mTOR goes up you build more muscle if mTOR goes up in a pro cancer environment You get a higher risk of cancer in a healthy environment. You just build more muscle. Does that mean mTORs it causes cancer? No, does that mean mTOR is always good to have up? No, it depends on the context It's very very complicated and so that's why when we look at studies and we're like oh this supplement Increases antioxidant capacity or or you know activity or this one does you know it reduces markers of stress Well, that doesn't necessarily mean, you know Ibuprofen reduces markers of inflammation very effectively take ibuprofen all the time You'll notice your joints will start to break down and you start to get problems because you need those markers, right? So it's very complicated and a lot of these supplements sell their products Based off these studies that are very narrow and they're almost all very narrow We want to look at the whole picture and have some length of time with people using that's why I use creatine creatine's been decades and It's been studied so many times thousands of studies peer reviewed that we're pretty sure we know what it does Well, especially a supplement like this like this would fall I'm assuming this I don't know anything really about it But I'm assuming that it falls under the performance category People are like that the biohacking right now that that whole community uses stuff like this So right, but I mean it's it's a it's more based off of enhancing performance It's not a supplement because most people are are not getting Whatever it is in their body and they need this it's sold as slows down the aging process reduces the negative effects of aging may increase Your your overall health and longevity may improve endurance. There was one study that showed An improvement in endurance with some athletes But that's how they're selling it right so and I like I've messed with everything and I've taken this We all did for a while. I didn't notice anything and that's happened a lot to me was there doesn't mean it doesn't work by the way That's just me But man, you you got it. Look you're trying to make your car go faster Like stop putting stickers on it in a spoiler like it's engine Let's focus on that first and then let's move down the line of the most important things like your four-cylinder You know gas efficient car and you're trying to slap a spoiler on it to make it have better performance You're wasting your money and your time Well, that's why I was asking that because the next step after you track after you do think big rocks like sleep and stuff like that The next thing would to be to actually find out if you're deficient in anything, right? There's something that your your body needs and you're missing whether it be vitamin D zinc or iron something that you're not Getting enough of magnesium and that can make a big difference in your sleep health performance like to me You're better off looking one two It's a lot cheaper by the way to most those supplements are relatively cheap to supplement with and you're giving your body Something that you've tested for they go. Oh, wow. I'm under I don't have enough vitamin D That is so important for so many different functions. Okay. Well, let instead of me going out and getting some Experimental supplement or new thing that bio hackers are talking about it's like I'm gonna go take I'm gonna discipline myself to take my vitamin D every single day since that will make a greater impact Yeah, and look I'm gonna read Doug. Just pulled up a study. So I'm gonna give you an example, right? So NMN supplementation promotes anti-aging MI RNA expression profile in the aorta of aged mice, okay What does that mean? What does that mean? That means so specific that just means that that means that there's this Anti-aging profile that we think is anti-aging and it looks like it promotes that and then here's the part the rest of the study predicting Epigenetic rejuvenation and anti-athorogenic effects predicting this is so a lot of probably words Yeah, and we don't know like we don't know if you if you change the profile that profile through Supplementation is that the same thing as it's a bit of a yeah, is that the same thing as looking at a young aorta? It's like three leaps. There's like three leaps in the huge leaves 15 words and there's three leaps in there None of it is human-related Hey, if you enjoyed that clip you can find the full episode here or you can find other clips over here and be sure to subscribe