 In this study, researchers examined synaptic dynamics between two types of neurons in the human brain, pyramidal neurons, and parvalbumin positive, p-valb, or somatostatin positive, SST, into neurons. They found that the synapses between these two types of neurons were distinctly different, with pyramidal neurons having more depressing synapses, while p-valb and SST neurons had more facilitating synapses. This suggests that the synaptic connections between these two types of neurons may be important for regulating neural activity in the human brain.