 My name is Andrea Ganna and I'm an associate professor at the University of Helsinki and a group leader at the Institute of Molecular Medicine in Finland. My team works on combining electronic health record and genetic data and devising new approaches to use this data for public health interventions. Some example on how this data it can be translated in something that has a direct impact to patients and public health is the use for example of polygenic risk score. So we are now testing with our collaborator in Estonia. We are testing the use of polygenic score in the clinical setting and look how polygenic scores can be used to identify individual attire risk for cardiovascular diseases and among women with breast cancer we are using polygenic score in combination with other genetic mutations to better understand the risk among the relatives of these women with breast cancer. We have a strong focus on privacy and ethical consideration when working on this data by guaranteeing that only qualified researcher can access the data and by using very secure computing environment which are not accessible to the outside world and are not connected to the internet. We think that the use of this data is a very large public health relevance and so we balance the public interest of the use with this data with ethical and privacy concern. In the COVID-19 genetic initiative which I've been leading we put together an international consortium to study the genetic determinants of COVID-19 not from the viral perspective but from our genome the human the host perspective and we found many genetic variants across the genomes that contribute to the risk of developing a severe form of COVID-19 and many of these genetic variants has led to the better understanding of biological pathways which can be used in combination with other studies that use different biological approaches to characterize the to characterize COVID-19 and the reason why some people develop a severe form of COVID-19. Italy has enormous potential to be leading in innovation especially for the amount of talent that is created across the country by the different university systems so I think that the talents are there what is really needed it's an investment in infrastructure and flagship projects that can attract the people from abroad to work in Italy so in other words I think that the potential are there but to really realize those potential we need some flagship project or some flagship effort that distinguish the research environment in Italy from other research environment in Europe.