 the current laboratory practices for determining the quality and safety of foodstuffs face, a constant expansion of the list of controlled indicators, particularly for the meat industry. To address these challenges, researchers have developed a highly sensitive and accurate method based on the multiple reactions monitoring MRM technique, which uses ultra-high performance liquid chromatography coupled with a triple quadrupole mass spectrometer. This method has been successfully applied to detect up to 5% of impurities of either beef or pork muscle tissue in freshly ground meat samples. These results suggest that the MRM protein assays presented in this paper could soon replace the ELISA methodology as a variant of multiplexed protein assay. This article was authored by D. V. Kostov, N. L. Bostrikova, I. M. Chernukha, and others.