 Invasive meningococcal disease, IMD, is a serious illness caused by new serious meningitis that affects infants, adolescents, young adults and has high mortality and morbidity rates. While IMD incidence peaks in both infants and adolescents, young adults, carriage rates are often highest in the latter age groups, increasing IMD risk and the likelihood of transmission. Effective vaccines are available for five of six disease-causing serogroups. Adolescents, young adults represent a significant proportion of cases, often have the highest carriage rate and have characteristically low vaccination adherence. Therefore, efforts should be focused on educating this population regarding long-term consequences of infection and the importance of meningococcal vaccination in prevention. This review describes the role of adolescents, young adults in meningococcal transmission and the clinical consequences and characteristics of IMD in this population. With a focus on countries with advanced economies that have specific meningococcal vaccination recommendations, the epidemiology of meningococcal disease and vaccination recommendations in adolescents, young adults will also be discussed. This article was offered by Cynthia Berman, Lydia Serra, Charles Nuttens, and others. We are article.tv, links in the description below.