 Hello! I am Mauno Viena from the Institute of Biomedical Technology University of Tampere Finland. I would like to draw your attention to a paper human mutation, which is written by myself, Johan Dendanen, Raymond Delklis and Richard D. Korten. The title of the paper is Kite lines for establishing local specific databases. Local specific databases, LSDPs, are databases for variations in specific individual genes and diseases. During years, the number of kite lines and recommendations have been published for how to establish, how to maintain and curate LSDPs. We have brought these kite lines together, we have revised and updated them. If you are interested in LSDP maintenance, the very first step is to find out whether there is a need for a new database. If the need exists, then a number of additional items have to be decided and taken care of. This includes, for example, ethical issues, the selection of database management system, decisions about the contents of the database, and then data collection. Once data collection is started, it is important to organize the data in the database in a systematic way. There, things like data models and ontologies should be used and taken care of. And finally, the data should be distributed and made available for the scientific community. Another paper written by Sally et al will appear about the creation of databases. Both these papers will be used as a basis for kite line recommendation by human variation project. The paper is intended for anybody interested on databases, LSDPs, how to create databases, how to collect information about variations and what kind of information is in LSDPs. As well as about the bioinformatics in variation field. I hope you find the paper interesting.