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Published on Apr 28, 2014
We are funded to produce biological microelectromechanical systems which recapitulate human tissue functionality. Such technology focuses on cultures of human cells within novel platforms that allow for assessment of physiologically correct functional outputs. Assays include measurement of electrical activity in neurons contractile activity in muscle and enzyme production in liver cells. By integrating such systems with microfluidic housings we aim to accurately model absorption distribution metabolism and elimination as well as toxicology of drugs in a human test system. The successful development of this model will accelerate drug trials and provide more predictive data pertaining to compound performance in humans.