 Namaskar! I am Dr. Tirthankar Mohanty. I am a practicing nephrologist in Manipal Hospital, Gajabat. This particular video is useful for someone who has been advised kidney biopsy by his treating nephrologist. So, today we will be talking in detail about kidney biopsy. Kidney biopsy basically means taking tiny pieces from the kidney with the help of an ultrasound and to examine that under a microscope. Usually kidneys have limited ways of expressing their distress when they are injured. They usually manifest their distress by rising serum creatinine or by licking protein in the urine. The blood pressure also may rise. So, there are no definite blood or urine test which can tell with certainty what disease is affecting kidney in order to establish the cause of the injury kidney biopsy is required. Kidney biopsy tells us about the disease affecting the kidney. It tells us about the severity of the injury. It also tells us whether the injury is permanent and unlikely to reverse with medications and it also predicts the response to treatment. Most important complications that you should be aware of is bleeding. When a living human being is poked with a needle that person is expected to bleed. Kidneys are highly vascular that is they receive approximately one fourth of the blood pumped by the heart. So, when the kidney is poked with a needle it is expected to bleed. In most of the cases the bleeding is not severe and it settles down on its own. But 1 in 100 may require blood transfusion for severe bleed. 3% may develop visibly red urine. Severe bleeding is even more rare. 1 in 10,000 may require a further procedure to control the bleeding and unfortunately this procedure etc will increase the cost of hospitalization as well as the duration of the hospital stay. There are a few absolute contra indications to the kidney biopsy that is there are a few strict no-nose for kidney biopsy. They are when the patient is uncooperative because the patient has to lie down still for the kidney biopsy and he has to hold his breath when asked. So, an uncooperative patient should not undergo kidney biopsy. Second thing is when the person is having an infected actively infected kidney or the overlying scheme is infected that also precludes kidney biopsy. Third thing will be when the person has some bleeding disorder like because of some disease or medications his or her blood is thin then that will also preclude a kidney biopsy. Kidney biopsy give a lot of useful information. So, in the absence of those information sometimes it's not possible to give optimum treatment. Either you will be giving getting under treatment or over treatment but yes your nephrologist will try his best to give you best supportive treatment in the absence of a kidney biopsy information. Kidney biopsy is a daycare or one day admission procedure prior to the kidney biopsy you will be evaluated in the OPD and your hemoglobin creatin will be checked whether you are receiving any blood thinner that will also be checked and after all this screening to avoid excessive bleeding you will be admitted for kidney biopsy. The procedure is done under real-time ultrasound guidance most of the complications occur within 24 hours that is approximately 98% of the complications occur within the next 24 hours. So many of the hospitals will discharge you after 24 hours. The biopsy report takes approximately 7 days to come and your appropriate treatment will start after your nephrologist receives the kidney biopsy. In the end I would like to tell that when an aphrologist takes a decision for kidney biopsy usually he weighs the benefit and risk and only then has advised you the kidney biopsy but after all it is a shared decision which the patient and doctor together has to make.