 The results of this systematic review suggest that older age, female gender, higher BMI, osteoporosis, depression, lower lumbar laudosis angle, higher spinal inclination angle, lower grip strength, lower back muscle strength, lower maximum stride, higher timed up and go, lower one leg standing time and slower normal gait speed are associated with locomotive syndrome, LS. This article was authored by Chisato Shimano, Koji Otoni, Ray Ono and others.