 Silk fibroin is a natural fibrous polymer with significant usage in regenerative medicine because of the growing interest in leftovers for silk biomaterials in tissue engineering. Regenerative medicine has received potential attention around the globe, with improving cell performances, one of the necessary ideas for the advancements. This article was authored by Asma Musfaira-Shawarand, Rajkumar Sekar, Levin Ambu Gomes and others.