 Clinical and Translational Science Award, CTSA, program is a consortium of nearly 60 academic medical research centers across the USA. Dissemination of the accrual to clinical trials, ACT, network began January 2018 across the consortium. Mixed methods assessed the spread and uptake of translational research innovation through July 1, 2019. This article was authored by Elaine H. Morato, Lindsay A. Lennox, Elena Ascendro and others.