 Coronavirus disease 2019, COVID-19, is a potentially serious acute respiratory infection caused by SARS-CoV-2. Since the World Health Organization, WHO, declared COVID-19 a global pandemic, the virus has spread to more than 200 countries with more than 500 million cases and more than 6 million deaths reported globally. Co-infections and superinfections are common among patients with COVID-19 and can lead to worse outcomes. Antibiotic resistance is a growing concern due to the increased use of antibiotics in hospitals and other healthcare facilities. Alternative antimicrobial agents should be used to combat the emergence of multi-drug resistant bacteria in COVID-19 patients. This article was authored by Carmelo Biondo, Elena Ponzo, Angelina Midori, and others.