 Hello everyone, I am Dr. Prashant Bhavna, I am a consultant rheumatologist and clinical immunologist at Manipal Hospital, J. Nagar, Bangalore. Today I would talk about vaccination in autoimmune inflammatory rheumatic disease. Many of them you know that infection is a major cause of morbidity and mortality in patients with autoimmune rheumatic disease. Invasive pneumococcal infections, influenza, herpes zoster, hepatitis B are the major vaccine preventable diseases. So, any patient who we are planning to start on antirheumatic drugs, we vaccinate them to boost immune system against those specific organisms. Ideal time is to give two weeks before we start antirheumatic drugs. Influenza vaccine is given once a year. Pneumococcal vaccines, they are two types. One is PCV13, which is T-cell dependent. It has to be taken once in lifetime. Another is PPSV23, which required a booster dose after 5 years and after 65 years of age. Other vaccine is herpes zoster, which has come recently to India. It is two-dose vaccine. One is at day zero and other is after two months of the first vaccine. It has to be given for the young woman if they are starting on anti-inflammatory medicines, particularly Tophacitinib, but ideally to be given after 50 years of age. The other vaccines, if you want to take like particularly hepatitis B, hepatitis C, particularly the healthcare professional who are at risk of getting the infection, you should consult an infectious disease specialist or a rheumatologist for the same. Thank you.