 Classical randomized clinical trials, RCTs, are considered the gold standard for proving drug efficacy, but randomized discontinuation trials, RDTs, also known as enriched trials, have been increasingly used in psychiatric maintenance studies. These trials use a dependent variable as a predictor, which is the same as the outcome, rendering them invalid. Additionally, RDTs may not increase statistical power or provide reliable results due to high dropout rates. Therefore, there is no evidence to support the use of RDTs in psychiatric maintenance designs. This article was authored by S. N. Gimi and Harry P. Selker.