 The study predicts that esophageal cancer, EC, prevalence, disability-adjusted life-years, dailies, and direct medical expenditure will increase in China from 2013 to 2030, with males experiencing a higher burden than females. The study highlights the need for policies to reduce the EC burden, as years of life lost account for over 90% of dailies. This article was authored by Yuan Yuanli, Zhu and Feng Siu, Yuxuan Gu and others.