 Ac we've been looking really at trying to understand how to deliver drugs to the brain. It's a problem that has affected neurosurgeons for a number of years because our brain, we're quite lucky in some respect, it has something called a blood-brain barrier. And that stops any toxins or any nasty bugs going up to the brain. But the idea is that you have a disease of the brain, the best way to treat it is to get drugs directly into your brain. So we have been working on a catheter design. We have tested this catheter in small animals and in large animals to get the best out of these catheters. So these catheters are very fine and they deliver through a sub-millimetre, half a millimetre wide catheter directly to discreet areas in the brain. The catheter is made of carbethane, a material that doesn't block and we have tested in the large animal to make sure that that catheter hasn't blocked. So the catheter is inserted into the brain under surgery and then a guide and guide tubing is connected to a port. And that port is based on a hearing aid so it's integrated just like a hearing aid behind the ear. But then this allows the patient to go home, come back in four weeks later, sit in a chair just like myself here today and have their treatment infused into the brain via our tubes, our catheter system, to be able to have their treatment. And this allows the patient to have a good quality of life whilst then coming back and having its treatment for either Parkinson's or for oncology. If you're unlucky enough to have a glioblastoma, a GBM, as an adult, the options are for removal of your tumour, resection. And then you were offered then radiotherapy and systemic drugs. The problem being with systemic drugs is that it delivers through the system in theory to be able to go around the body and then also affect the tumour area. This reduces the amount of drug in contact with the ever-growing tumour. Whereas if you have a tumour that's been resected and you have a potential catheter system, a tube directly in the area, per number of your tumour, you can directly target drugs. And for children, so they either have brain tumours that are non-operable in a really discreet area in the brainstem, which unfortunately if you diagnose with, you have no options to be able to remove it by surgery is too difficult. It's by a place called the nerve, optic nerve, and it's deemed to be too severe to have a surgery and removal. But using our catheter systems, we have the ability to be able to deliver to a discreet area and local chemotherapy that will be able to halt the progression of the tumour. It doesn't have the nasty side effects like systemic feel of losing hair because it's not going around the rest of the body, it's only really localised and trapped in the brain.