 This study investigated the effects of hydrophilic extract of nasturtium aficinol on ethylene glycol-induced renal stone in male wister rats. The results showed that the extract had no significant effects on urinary and chemical parameters effective in calcium-oxylate stone crystals in rat, however it did have a preventive effect on renal stone formation when administered at a low dose. This article was authored by Sidrala Marabi, Eslam Askapur, Farhad Marabi, and others.