 This paper presents a new method for creating pickering double emulsions which can then be used to create multi-compartmental metal organic frameworks, MOF, microreactors. These microreactors have the potential to be used in synthetic biology and metabolic engineering applications, such as cascade reactions. The authors demonstrate how these microreactors can be used to improve the performance of two different chemical processes, namely olefin metathesis and glucose oxidation. They show that the multi-compartmental microreactors outperform homogenous mixtures of the same components, demonstrating the potential of this technology. This article was authored by Dan Ping Tian, Rui Ping Hao, Xiu Ming Zhong, and others.