 This systematic review aims to summarize the current evidence on the impact of the COVID-19 pandemic on anxiety levels among children and adolescents in Europe. It will evaluate the risk of bias in non-randomised studies of exposure, robinsie, assess the certainty of evidence for each outcome using the grade approach, and conduct subgroup analyses, sensitivity analyses, publication bias analyses, and meta-aggression analyses, if applicable. This article was authored by Helena Ludwig-Wals, Indra Danheim, Lisa M. Fadenhauer, and others.