 Policistic ovary syndrome, PCOs, is a common condition affecting up to 1 in 5 women of reproductive age. It has significant clinical implications including reproductive, metabolic, and psychological features. PCOs is a heterogeneous condition with varying phenotypes depending on life stage, genotype, ethnicity, and environmental factors. Obesity-induced insulin resistance exacerbates all the features of PCOs. Therapy should focus on lifestyle improvement aimed at normalizing insulin resistance, improving androgen status, and aiding weight management. Modest weight loss has been shown to improve many features of PCOs. Comprehensive evidence-based guidelines are needed for early diagnosis, investigation, regular screening, and treatment of this common condition. This review primarily focuses on the cardiometabolic and psychological features of PCOs. This article was authored by Dixie, TdH, and Moranel. We are article.tv, links in the description below.