 In this review, we discussed the migration and homing ability of mesenchymal stem cells, MSCs, and MSC-like cells and factors influencing this. We also discussed studies related to the mechanism of migration and homing and the approaches undertaken to enhance it. Finally, we described the different methods available and frequently used to track and identify the injected cells in vivo. This article was offered by Abhishek Sonny and Katharine M. Verfali.