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nanoHUB-U Nanobiosensors L3.9: Sensitivity - Amperometric Sensors - Beating the Diffusion Limit

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Published on Feb 19, 2014

Table of Contents:
00:09 Lecture 3.9: Amperometric Sensors - Beating the diffusion limit by Nanogap Amperometry
01:08 Outline
01:47 Glucose detection by amperometry
03:03 Essence of Amperometric Detection
03:46 Oxidation-Reaction with Diffusion
06:27 Beating diffusion limit by Redox Cycling
10:54 Beating diffusion limit by Redox Cycling
11:57 Balance the Flux, find the densities
14:10 Flux recycling for Planar Electrodes: Power of nanoscale detection
15:26 Flux recycling: arbitrary electrode geometry
16:46 A general formula for flux recycling
18:04 Finite gap Amperometry: Examples
19:24 Finite gap Amperometry: Examples
20:09 DNA Detection by Amperometry
21:57 Amperometric DNA Detection
23:04 DNA detection by nanogap amperometry
24:43 DNA detection by nanogap amperometry
25:27 DNA sequencing by nanogap amperometry
26:28 Conclusions

This video is part of the nanoHUB-U course "Principles of Electronic Nanobiosensors". (https://nanohub.org/courses/PEN)

This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.

For more details see http://nanohub.org/u

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