 Organic photothermal co-crystals are a type of hybrid material composed of two or more components with different physical properties. They have been widely used in various fields such as photoacoustic imaging, seawater desalination, and photothermal therapy due to their unique characteristics. Despite the potential benefits of this material, there has not yet been a comprehensive review of its development and application. In this paper, the authors systematically summarized the current research on organic photothermal co-crystals, including their classification, photothermal conversion mechanism, and applications. By understanding the underlying principles behind the formation of organic photothermal co-crystals, we can better utilize them for future applications. This article was authored by Yutao Chin, Mingpingzhu, Siniwan, and others.