 This study investigated the effects of turkey tail, TT, mushroom extract on the growth of toxoplasma gondii tachyzoids in vitro. The results showed that the extract had a significant inhibitory effect on the parasite's growth, with an IC50 value of 5.98 GML. Additionally, the extract caused morphological changes in the parasite, such as disruption of mitochondrial membrane potential and production of superoxide and reactive oxygen species. These findings suggest that TT mushroom extract may have potential as a novel therapeutic agent for treating toxoplasmosis. This article was authored by Homer Nath Sharma, Jonathan Catrett, the Gitchie Destiny Noir Co-Otcher, and others.