 Econite is commonly used in Chinese and Ayurvedic medications in Bhutan, but its narrow therapeutic index increases the risk of significant cardiotoxic and neurotoxic events due to intentional or unintentional ingestion. This case series presents two cases of bradycardia, hypotension, and reversible conduction defects caused by prescribed Econite-based Bhutanese traditional medicines for different therapeutic goals, resulting in cardiac dysrhythmias.