 In this study, the authors assess changing symptom profiles associated with different SARS, CoV-2 variants from May 2020 to March 2022 in England. Using data from the React 1 study, they find that Armacran infection is more often associated with cold and influenza-like symptoms and less with loss of taste and smell. This article was authored by Matthew Whitaker, Joshua Elliott, Barbara Bodinea, and others.