 Acenobacter bamanii is a major cause of hospital-acquired infections and its outer membrane vesicles, OMVs, have been found to play a role in its pathogenicity. In this study, researchers examined the differences in OMVs produced under normoxic and hypoxic conditions. They found that OMVs from hypoxic conditions had a different protein profile and caused more severe damage to lung cells than those from normoxic conditions. Additionally, they observed that OMVs from hypoxic conditions increased the ability of A. Bamanii to invade lung cells, suggesting that hypoxia may enhance the pathogen's ability to spread. This article was authored by Satio Suzuki, Fani Subsem Wang, Kujing Arita, and others.