 The fusion reaction involving proton, P, and boron, 11b, has unique advantages over deuterium tritium, DT, fusion in terms of number of neutrons generated and availability of the fuel components. Here the authors demonstrate the P, 11b, fusion reaction in a magnetically confined plasma at the large helical device. This article was authored by R. M. McGee, K. O. Gower, K. Tajima, and others.