 I am Dr. Mithesh Chetty, Head of Department and Consultant, Department of Medical Genetics, Manipal Hospital. This department is 22 years old in Manipal Hospital. We are having in-house facility of counseling as well as a high-end genetic laboratory. Most cancers are idiopathy, so that is not heredity. But small portion of cancer is familiar. Breast cancer is the second common cause of cancer. In every woman, they have a risk of developing breast cancer around 12% sometime in their life. Heredity breast and ovarian cancer syndrome is a genetic condition where there is increased risk for breast cancer in males and females, ovarian cancer, pancreate cancer and certain other cancers like prostate and skin cancer like melanoma. There are two genes are there, which is known as BRCA1 and BRCA2. More than these two genes, there are other 22 genes are there which is associated with heredity breast and ovarian cancer which we call as HBOC. Only 5 to 10% of breast cancers are hereditary cancers. When a person has this cancer, then it has a 50% chance of passing into sex generation. Now again, cancer, the genetic is little different. So once the individual person carries this mutation, doesn't mean that person will develop a cancer. It just says that the chance of developing a cancer is more than the population. So now we have a treatment which is immunotherapy. If they are positive for BRCA1 and BRCA2, they have a different immunotherapy. So earlier this test was only for the actress people, but as the genetic is evolving, it has a benefit to the patient also. In cancer, we have to always test the affected individual. In the cancer, we use the technology which is called as NETGEN sequencing, which is called as NGS, where we sequence multiple genes together. So as I told you, there are 24 genes associated with HBOC. We can sequence the multiple gene together and we can see those variants, whether those are present in the individual or not. Another thing which is important in cancer is counseling. Counseling is very important. The patient is going to benefit and what is the actress people are going to benefit and not that we can say directly test the affected individual. So counseling is very important. We are in an era where we are moving towards precision medicine. Right now what we are giving treatment is one sign which fits all. But in precision medicine, the medicine which is designed specific for the genetic changes, the lifestyle and the environment factor, it will give the maximum benefit. So the precision medicine is for nothing but the right medicine for the right person at right dosage at right time. In Manipura Hospital, we have NETGEN sequencing and we have a counseling facility along with our cancer team. It helps in the better patient care.