 I'm interested in why males and females respond differently to a heart attack and the mechanisms or the reasons why they would respond differently. Typically when women experience a heart attack, they first of all experience different symptoms and so they're less likely to recognize that they're having a heart attack and in so doing they're more likely to take longer to reach hospital so that time there is crucial for responding to the heart attack. Secondly, once they reach hospital the research shows that they have worse outcomes than males and this is potentially down to worse treatments or less optimal treatments for females compared to males. My research has been focused on the role that the brain has in driving these outcomes after a heart attack. So the brain sends signals to the heart and to the cardiovascular system and in so doing it responds to the heart attack sometimes appropriately but sometimes not and treatments such as beta blockers target this activity from the brain and it's been optimized in males but we're not sure how effective it is in females. My hope would be that in the future that females will, well greater awareness around the differences between males and females following a heart attack so that there's more recognition that females do suffer as much as males do and then secondly that treatments once again are optimized further so that outcomes following a heart attack are improved both in males and in females.