 This case study demonstrates how the combination of certain medications can lead to adverse side effects such as anxiety, agitation, and hyperactivity. In this particular instance, the patient was taking three different drugs, acetalopram, trasodone, and selicoxib, all of which are known to have potential interactions when taken together. This case highlights the importance of understanding the potential interactions between various medications and the need for caution when combining them. This article was authored by Toshinori Shirata, Shinji Yeno, Keisuke Noto, and others.