 This study investigated the prevalence of carbapenam-resistant apex strains among broiler chicken flocs affected by colobacillosis. The researchers identified 154 apex strains out of 750 samples, with 8.4 percent being resistant to carbapenams. Additionally, five of these strains harbored the MCR-1 gene, which confers resistance to the last line of defense against bacterial infections. The authors concluded that the improper use of antibiotics in poultry production systems is contributing to the emergence of pathogens such as carbapenam-resistant apex strains carrying the MCR-1 gene. This article was authored by Muhammad Usman, Muhammad Hidayek Rasool, Mohsin Kershid, and others.